Evaluation of treatment outcomes with passive presurgical infant orthopaedics in patients with non-syndromic cleft lip and or palate: A systematic review conducted according to PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions

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ABSTRACT

Aim

The primary goal of the present comprehensive systematic review is to assess the treatment results attained through PSIO in individuals with NSCLP, as well as to explore its effectiveness. This will be accomplished by examining a range of existing published studies that focus on patient groups who have undergone PPIO.

Material and methods

A comprehensive search strategy was devised by a single author for each database without language restrictions. The databases searched were PubMed, Cochrane library Google Scholar, Web of Science and Scopus. The search period was limited to the years 2001 to 2023. Duration and study design filter was used. Furthermore, conference proceedings, abstracts, and reference lists of relevant studies were sought to obtain additional records.

Results

Titles, abstracts, and full texts of studies identified from the literature search were screened by two authors independently and then combined together. The information from the short-listed studies that were considered were: first author, year of publication, the groups, type of intervention and outcome parameters like maxillary arch collapse, speech defects, facial aesthetics, anthropometry and oral motor skills, transverse and maxillary arch relationship and the results of these studies was tabulated. Bias was analysed using the Cochrane’s Risk of Bias tool (RoB 2). Total 8 articles which met the inclusion criteria were included in this review. The was no statistically significant difference in the treatment outcomes achieved after performing PSIO in patients with UCLP.

Conclusion

The examined protocols for passive presurgical infant orthopaedics (PPIO) in individuals with CLP typically did not reveal notable treatment outcomes when compared to a lack of treatment across a range of domains. These domains encompass feeding patterns, facial aesthetics, maxillary dentoalveolar factors, cephalometric measurements, speech and language-related aspects, dental arch alignments, economic assessments, as well as occurrences of adverse effects or complications associated with applied appliances or procedures.

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