Oral squamous cell carcinoma in the paediatric patient: a literature review

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ABSTRACT

Aim

Paediatric Oral Squamous Cell Carcinoma (OSCC) is rare, but its incidence is increasing, bringing forward
the issue of the common pathogenic factors. The aim of this study is to verify the actual incidence of oral carcinoma reported
in paediatric patients up to the age of 15 by thoroughly reviewing the available literature. Setting this cut-off age has allowed
us to emphasise possible risk factors other than those always associated with the onset of this neoplasia, which are not
present in this age bracket yet.

Methods

In the first stage of the research, generic key words concerning OSCC in
childhood were entered into two search engines. In the second stage, terms related to predisposing diseases connected to
childhood oral carcinoma and those initially found were searched.

Results

The literature review consisted of 55
documented cases from 1894 to 2011, of which 15 were part of complete published case reports.

Conclusion

Paediatric
OSCC, though uncommon, is not rare. The review has strongly highlighted the need to carry out an objective, thorough and
standardised examination of the child's oral cavity, especially when systemic predisposing diseases, such as Epidermolysis
bullosa, Xeroderma pigmentosum, Juvenile papillomatosis and Fanconi's anaemia, are present.

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