Title:  Preeruptive intracoronal radiolucency caused by resorption: report of a case

Abstract:  The aim of this study were to describe a clinical case of an intracoronal radiolucent lesion detected in unerupted mandibular first molar and to discuss the aetiology of the present case utilising immunocytochemical staining of the removed tissue from the lesion. In contact with the enamel surface and near the dentine fragment of the removed tissue, numerous multinucleated giant cells were observed. Immunocytochemistry revealed that the giant cells had immunoreactivity to cathepsin-K, which is known to indicate resorptive activity of cells. It was assumed that mechanical stress and microscopic breakdown of a protective layer of enamel would cause externally the present coronal resorption of unerupted molar.