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The effect of nasal midazolam premedication on parents-child separation and recovery time in dental procedures under general anaesthesia

Type:  Articles

Pubblication date:  /1/2015

Authors:  T. Eskandarian*, S. Arabzade Moghadam**, S. Reza Ghaemi***, M. Bayani**

Language:  English

Institution:  Department of Paediatric Dentistry, Dental School, Shiraz University of Medical Sciences, Shiraz, Iran *Assistant Professor **Post-graduate Student ***Anesthesiologist

Publication:  European Journal of Paediatric Dentistry

Publisher:  Ariesdue Srl

Keywords:  Nasal midazolam; Premedication; Recovery time; Separation.

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Title:  The effect of nasal midazolam premedication on parents-child separation and recovery time in dental procedures under general anaesthesia

Abstract:  Aim For many children medical and dental procedures, unfamiliar dental staff and treatment places are disturbing and stressful. Stress in children often makes them uncooperative. General anaesthesia is indicated for anxious uncooperative children or those who are disabled, immature or too young to undergo dental treatment by other means. Moreover parents’ separation while entering the operative room is a traumatic experience for children. Thus premedication such as midazolam is recommended to decrease child’s stress. In these situations the increased recovery time was considered as one of the midazolam side effects. There is no study that evaluated the effect of midazolam both in parents-child separation and recovery time in long dental procedure. The purpose of this study was to evaluate the effect of nasal midazolam premedication with placebo on parents-child separation and recovery times in uncooperative paediatric patients undergoing long-lasting general anaesthesia for dental procedures. Materials and methods Study design: This randomised, double-blind study was done on 60 uncooperative patients (ASA physical status I or II) aged 2-4 years who were scheduled for general anaesthesia for dental treatment. Group A received 0.2 mg/kg intranasal midazolam as premedication, and group B received the same volume of intranasal placebo 20 minutes before entering the operating room for general anaesthesia. General anaesthesia was done with the same method for all patients, then parent-child separation and recovery times were compared between the two groups. Statistical analysis: Statical significance was set at P≤0.05. Statically analysis was performed using SPSS version17.Chi-squared and student t-tests were applied to analyse the data. Results We found significant differences in parents-child separation assessment between two groups. Nasal midazolam premedication had a positive effect on parents-child separation; but there was no significant difference between the two groups in terms of recovery time. Conclusion Premedication of nasal midazolam before induction of general anaesthesia did not prolong recovery time but made the separation of children from their parents easier by showing a better behaviour.

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