Gingival myofibroma. A case report

Authors:

ABSTRACT

Aim

The Myofibroma (MF) is a benign mesenchymal tumor frequently observed in the skin and subcutaneous
tissue of the head-neck region. It is described mainly in infants with congenital forms and, in early childhood, with acquired
forms. Less often, it can be observed in adolescents and adults. The location of a MF in the oral cavity is occasional and
differential diagnosis must be established with other benign and malignant neoplasms, high or low grade, of the oral
mucosa. The histology of the myofibroma shows a biphasic growth pattern: elongated spindle cells with eosinophilic
cytoplasm, in the borders, polygonal cells arranged in a palisading pattern, with hyperchromatic nuclei, in the central
portions. The diagnosis of MF, usually made after excision of the neoformation, is obtained by means of
immunohistochemistry, in which there is positivity for vimentin and alphaactine smooth muscle antibodies and negativity for
keratin, S-100, EMA (Epithelial Membrane Antigen) antibodies. The treatment is surgical; the prognosis is generally good with
low rates of recurrence after excision. CASE REPORT: The authors describe a case of MF in a 16-year-old male subject, that
came to their observation for the growth of a considerable mass attached to the gingival mucosa, describing the therapeutic
strategy.

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